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Fig. 5 | Malaria Journal

Fig. 5

From: Immunogenicity of the Plasmodium vivax merozoite surface protein 1 paralog in the induction of naturally acquired antibody and memory B cell responses

Fig. 5

Memory B cell response to the PvMSP1P-19 antigen. a The level of the memory B cell (MBC) response to the PvMSP1P-19 antigen and tetanus toxoid in individual PBMCs from 9 months after P. vivax infection were determined by ELISPOT (n = 11). The frequencies of MBCs are expressed per million cultured PBMCs. Each symbol represents the MBC number for one individual. The line reflects the median value. SPM, spots per million. b The correlation between the ELISA and ELISPOT responses to the PvMSP1P-19 antigen. The data are shown for 11 subjects at 9 months after recovery from P. vivax infection. The numbers of subjects who were double-positive (top left), ELISA-positive but ELISPOT-negative (bottom left), ELISA-negative but ELISPOT-positive (top left) or double negative (bottom right) are shown

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