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Table 1 Effect of initial P. vivax stage on pLDH-ELISA IC50 results

From: Measuring ex vivo drug susceptibility in Plasmodium vivax isolates from Cambodia

Drug

Spearman correlation test

Mann–Whitney U test

P value

for IC50 and EM ratio

EM ratio ≥ 4

EM ratio ≤ 0.25

N

coefficient

P-value

N

median IC50

N

median IC50

DHA

57

− 0.34*

0.009*

11

2.6

12

7.5*

0.008*

AS

56

− 0.46*

< 0.001*

11

2.9

11

9.4*

< 0.001*

CQ

46

− 0.12

0.445

12

23.8

4

28.1

0.716

PPQ

52

− 0.01

0.922

12

104.3

7

99.5

0.612

LUM

34

− 0.42*

0.014*

4

5.6

7

25.4*

0.023*

DOX

35

− 0.70*

< 0.001*

5

12,680

9

42,667*

0.003*

ATM

23

− 0.12

0.593

3

0.61

7

2.0

0.137

MQ

27

− 0.39

0.046*

4

161.2

4

203.7

0.083

  1. * Statistical significance