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Fig. 5 | Malaria Journal

Fig. 5

From: Statistical methods to derive efficacy estimates of anti-malarials for uncomplicated Plasmodium falciparum malaria: pitfalls and challenges

Fig. 5

Cumulative failure estimates for drugs with different terminal elimination half-lives. The solid line represents K–M cumulative failure probabilities and the dotted line represents the drug levels with hypothetical units presented on the right y-axis. Drug B (blue) has a longer elimination half-life and the recrudescent failures are more patent after day 21 compared to drug A (red) with a short half-life and recrudescences being observed after day 7

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Malaria Journal

ISSN: 1475-2875

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