Table 1 Single nucleotide polymorphisms (SNPs) in the gene encoding lactate dehydrogenase (LDH) of Plasmodium falciparum
From: Global sequence diversity of the lactate dehydrogenase gene in Plasmodium falciparum
Allele | Isoform | Nucleotide position (corresponding amino acid position) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
36 (12) | 73 (25) | 85 (29) | 259 (87) | 399 (133) | 407 (136) | 450 (150) | 451 (151) | 513 (171) | 560 (187) | 563 (188) | 783 (261) | 814 (272) | 858 (286) | 891 (297) | ||
L1a | LDH-1 | TCA S | CAG Q | GGA G | GGA G | GTA V | TTA L | TTA L | GGT G | CCA P | GTT V | CTT L | TCA S | GAT D | GTT V | GAG E |
L1b | TCG S | – | – | – | – | – | – | – | – | – | – | – | – | – | GAA E | |
L1c | – | – | – | – | – | – | – | – | CCC P | – | – | – | – | GTC V | – | |
L1d | – | – | – | – | – | – | TTG L | – | – | – | – | – | – | – | – | |
L1e | – | – | – | – | – | – | – | – | – | – | – | TCG S | – | – | – | |
L2 | LDH-2 | – | – | – | – | – | – | – | – | – | – | – | – | AAT N | – | – |
L3 | LDH-3 | – | AAG K | – | – | – | – | – | – | – | – | – | – | – | – | – |
L4 | LDH-4 | – | – | CGA R | CGA R | GTC V | – | – | CGT R | – | GGT G | – | – | – | – | – |
L5 | LDH-5 | – | – | – | – | – | TCA S | – | – | – | – | CCT P | – | – | – | – |