Fig. 2From: Differential induction of malaria liver pathology in mice infected with Plasmodium chabaudi AS or Plasmodium berghei NK65Hepatic haemozoin levels, oxidative damage and fibrosis in liver tissue of P. berghei NK65 or P. chabaudi AS infected mice. Hz content in liver tissue (pmol Hz/mg liver tissue) of P. berghei NK65 or P. chabaudi AS infected C57Bl/6J mice at day 8 and 10 post infection (a). Hepatic mRNA expression levels of TNF-α in non-infected and infected mice at day 8 or day 10 post infection determined by quantitative RT-PCR and normalized to 18S ribosomal RNA levels (b). OH-proline content (μg/mg protein) in non-infected and infected mice at day 8 or day 10 post infection (c); MDA content (pmol/liver) in non-infected and infected mice at day 8 or day 10 post infection (d). n = 6 mice/for each time point and group. *p < 0.05; **p < 0.01; ***p < 0.0001 vs Control; °°p < 0.05; °°°p < 0.01 P. berghei NK65 vs P. chabaudi ASBack to article page