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Fig. 4 | Malaria Journal

Fig. 4

From: A novel immortalized hepatocyte-like cell line (imHC) supports in vitro liver stage development of the human malarial parasite Plasmodium vivax

Fig. 4

Plasmodium vivax infection in HC-04 cell and immortalized hepatocyte-like cell (imHC) cultures. Hepatocytes were grown in an eight-well plate at a density of 3 × 105/well. Each well was infected with 3 × 105 salivary gland P. vivax sporozoites. Infected hepatocytes were harvested, and the exoerythocytic forms were counted in an indirect immunofluorescence assay on day 4 post infection. The per cent sporozoite infectivity was determined by comparing the number of infected hepatocytes to the total number of inoculated sporozoites. All data are shown as means ± standard errors of the means of three independent experiments from three different P. vivax isolates. The Mann–Whitney U test was used to evaluate the p value. ns non-significant (p > 0.05)

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