Efficacy of artesunate–amodiaquine, dihydroartemisinin–piperaquine and artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Maradi, Niger

Table 3 Parasite clearance indicators

	AS–AQ		DHA–PPQ		AM–LM		p
	Median	[IQR]	Median	[IQR]	Median	[IQR]	p
Clearance rate constant (h)	0.27	[0.22–0.32]	0.26	[0.21–0.31]	0.25	[0.20–0.30]	0.124
Slope half-life (h)	2.61	[2.15–3.18]	2.68	[2.23–3.23]	2.77	[2.29–3.42]	0.124
Time to clearance 50% of parasitaemia (h)	9.10	[4.89–12.89]	8.79	[4.87–12.26]	10.10	[7.49–13.93]	0.001
Time to clearance 99% of parasitaemia (h)	24.41	[20.10–28.97]	23.79	[19.94–29.37]	26.31	[22.64–32.00]	0.001

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