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Table 4 Adverse events during the follow-up period

From: Efficacy of artesunate–amodiaquine, dihydroartemisinin–piperaquine and artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Maradi, Niger

 

AS–AQ

(N = 221)

DHA–PPQ

(N = 221)

AM–LM

(N = 221)

p

n

(%)

n

(%)

n

(%)

Fever

90

(40.7)

94

(42.5)

94

(42.5)

0.906

Cough

31

(14.0)

36

(16.3)

22

(10.0)

0.141

Rhinorrhoea

20

(9.1)

27

(12.2)

17

(7.7)

0.255

Diarrhoea

19

(8.6)

14

(6.4)

15

(6.8)

0.624

Conjunctivitis

11

(5.0)

7

(3.2)

15

(6.8)

0.216

Pyoderma

12

(5.4)

6

(2.7)

6

(2.7)

0.211

Vomit

8

(3.6)

6

(2.7)

5

(2.3)

0.684

Anorexia

6

(2.7)

4

(1.8)

1

(0.5)

0.173

Asthenia

1

(0.5)

0

(0.0)

0

(0.0)

0.367

Abdominal pain

3

(1.4)

0

(0.0)

1

(0.5)

0.172

Arthralgia

1

(0.5)

0

(0.0)

0

(0.0)

0.367

Headache

1

(0.5)

0

(0.0)

0

(0.0)

0.367

Convulsions

1

(0.5)

0

(0.0)

0

(0.0)

0.367

Hepatomegaly

0

(0.0)

1

(0.5)

0

(0.0)

0.367

Splenomegaly

1

(0.5)

2

(0.9)

1

(0.5)

0.778

Other events

34

(15.4)

40

(18.1)

45

(20.4)

0.457