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Fig. 4 | Malaria Journal

Fig. 4

From: Humanized DRAGA mice immunized with Plasmodium falciparum sporozoites and chloroquine elicit protective pre-erythrocytic immunity

Fig. 4

AMA1-specific, HLA-A2-restricted human CD8 T cells localize in the liver of CPS-CQ immunized DRAGA mice. DRAGA mice (n = 7) were immunized with CPS-CQ three times at 2 weeks interval. Three weeks after the last immunization, the cytokine response of splenic and liver human CD8 T cells to stimulation with AMA406–414 synthetic peptide was measured by Luminex. Data show values of TNF, IFNγ, and IL-5 in individual mice

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