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Table 1 P. vivax proteins selected for NAPPA array

From: Self-assembling functional programmable protein array for studying protein–protein interactions in malaria parasites

Annotation

Pv gene ID

Time transcriptiona

Localization

Proteome datac

Fragments

Regions expressed

Target P. vivax proteins

 Merozoite surface protein 1 (PvMSP1)

PVX_099980

TP7

Merozoite surface

X

2

1350D-F1723; 761G-E1349

 Merozoite surface protein 4 (PvMSP4)

PVX_003775

TP7

 

1

30I-S248

 Merozoite surface protein 8 (PvMSP8)

PVX_097625

TP2

X

1

24G-Y462

 Merozoite surface protein 10 (PvMSP10)

PVX_114145

TP7

 

1

30L-A459

 6-Cysteine protein 41 (Pv41)

PVX_000995

TP7

X

1

19A-Q383

 6-Cysteine protein 12 (Pv12)

PVX_113775

TP7

X

1

27T-G336

 Asparagine rich protein (PvARP)

PVX_090210

TP7

X

1

16C-V284

 Thrombospondin-related protein (PvTRAMP)

PVX_123575

TP8

Apical/merozoite surface

 

1

24K-I300

 Merozoite surface protein 5 (PvMSP5)

PVX_003770

TP8

Micronemes/apical

X

1

22R-I362

 Apical merozoite antigen 1 (PvAMA1)

PVX_092275

TP8

X

2

43P-E343; 43P-L487

 Duffy binding protein 1 (DBP1)

PVX_110810

↓ transcriptionb

 

3

26E-C217; 198T-D524; 521T-T1000

 Reticulocyte-binding protein 1a (PvRBP1a)

PVX_098585

TP8

 

4

582E-E1457; 1549F-G1758; 1880S-R2229; 2245S-E2832

 Rhoptry neck protein 1 (PvRON1)

PVX_000945

TP7

Rhoptry neck protein

 

1

25K-R772

 Rhoptry neck protein 2 (PvRON2)

PVX_117880

TP7

X

2

735G-L1560 and 1554L-V2203

 Rhoptry neck protein 5 (PvRON5)

PVX_089530

TP7

X

1

23F-W500 (PvRON5A); 50N-P1158 (PvRON5C)

 Rhoptry neck protein 4 (PvRON4)

PVX_091434

TP7

 

1

25F-I756

 Rhoptry-associated protein 1 (PvRAP1)

PVX_085930

TP7

Rhoptries

 

1

2T-Y633

 Rhoptry-associated protein 2 (PvRAP2)

PVX_097590

TP7

X

1

22H-H382

 High molecular weight rhoptry protein 3 (PvRhopH3)

PVX_098712

No data

 

1

21Q-F599

 Rhoptry associated membrane antigen (PvRAMA)

PVX_087885

TP7

Rhoptry body protein

X

1

21F-G710

Prey P. vivax protein

 6-Cysteine protein 12 (Pv12)

PVX_113775

TP7

Merozoite surface

X

1

27T-G336

  1. aTranscription data from time points (TP) 1–9 of 3 vivax malaria isolates [82]
  2. bLow transcriptional levels in all time points measured (TP1–TP9) [82]
  3. cData from proteomic analyses [51, 55]
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Malaria Journal

ISSN: 1475-2875

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