From: Pharmacokinetics of mefloquine administered with artesunate in patients with uncomplicated falciparum malaria from the Brazilian Amazon basin
Parameter
Value
Cmax (µg/ml)
3.1 (1.5–3.8)
AUC0−t (µg/ml h)
480 (330–60)
AUC0−∞ (µg/ml h)
484 (363–777)
Cl/f (liters/kg/h)
0.04 (0026–0058)
V/f (liters/kg)
13.2 (6–19)
t1/2 (days)
10.1 (7–16)