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Table 2 Prevalence of Pvdhfr, Pvdhps, Pvmdr1, and Pvk12 allelic variants in Nouakchott and Atar, Mauritania

From: Assessment of drug resistance associated genetic diversity in Mauritanian isolates of Plasmodium vivax reveals limited polymorphism

Gene

Allelic varianta

Nouakchott n/N (%)

Atar n/N (%)

Pvdhfr

IPFSTSI (wild-type)

126/154 (81.8)

44/45 (97.8)

IPFRMSI

28/154 (18.2)

0

IPFSTNI

0

1/45 (2.2)

Pvdhps

SAKAV (wild-type)

93/93 (100)

37/37 (100)

Pvmdr1

YF (wild-type)

110/115 (95.7)

76/79 (96.2)

FF

5/115 (4.3)

1/79 (1.3)

YL

0

2/79 (2.5)

Pvk12

V552 (wild-type allele)

59/59 (100)

48/48 (100)

552I

0

0

  1. n number of isolates with the given allelic variant N total number of isolates analysed
  2. aAllelic variants are based on the following codons: 13, 33, 57, 58, 61, 117, and 174 for Pvdhfr; 382, 383, 512, 553, and 585 for Pvdhps; and 976 and 1076 for Pvmdr1. The amino acid substitution V552I in Pvk12 was suggested to be a potential marker for artemisinin-resistant P. vivax in Cambodia [39]