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Table 1 Study profile of index cases and FTAT investigation, by transmission and importation category

From: Malaria case investigation with reactive focal testing and treatment: operational feasibility and lessons learned from low and moderate transmission areas in Amhara Region, Ethiopia

 

Low transmission, low importation villages

6 villages: Ancharo, Choresa, Dehina Sositu, Hardibo, Ketie, Zengoba Denguma

Low transmission, high importation villages

3 villages: Berhan Chora*; Enashenifalen; Yeginid Lomi

High transmission, low importation village

1 village: Kumar

Aftit*

Total

10 villages

2015 population estimates

34,294

23,684

3666

61,644

 Index cases

  Passively detected P. falciparum/mixed, n

23

156

228

407

  Investigated, n (%)

18 (78.3)

141 (90.4)

61 (26.8)

220 (54.1)

  Investigated cases with travel history in past 30 days, n (%)

2 (11)

126 (89.4)

0 (0)

128 (58.2)

  Investigated cases with no travel history in past 30 days, n (%)

16 (89.0)

15 (10.6)

61 (100.0)

92 (41.8)

  Interval parasite index (per 1000 population in the high transmission season)

0.67

6.6

62.2

6.6

FTAT investigation

 Index case HH

  Individuals in HHs, n (excluding index cases)

74

529

270

873

  Individuals tested, n (%)

66 (89.2)

503 (95.1)

203 (75.2)

772 (88.4)

  RDT positivity, n (%)

5 (7.6)

7 (1.4)

25 (12.3)

37 (4.8)

 Neighbouring HH

  HHs visited, n

112

254

328

694

  Individuals in HHs, n

529

1113

1341

2983

  Individuals tested, n (%)

467 (88.3)

1002 (90.0)

1002 (74.7)

2471 (82.8)

  RDT positivity, n (%)

2 (0.4)**

8 (0.8)

80 (8.0)**

90 (3.6)

  1. FTAT, focal test and treat; HH, household
  2. * In Berhan Chora and Kumer Aftit, the FTAT procedures were modified on 1 November, 2014 because it was not possible to complete case investigations for every index case. If the index case had a travel history, only the index case household was visited for the case investigation rather than the index case household plus up to 10 neighbouring households
  3. ** Significant P value comparing RDT positivity in Index HH and Neighbouring HH (P < 0.05)