Table 3 Accuracy of RDT and peripheral thick blood smear in comparison with placental tissue impression smear for detecting placental malaria infection in 197 women at delivery
Placental tissue impression smear | Accuracy measure in % (95% CI) | ||||
|---|---|---|---|---|---|
Positive | Negative | Total | |||
Per thick blood smear | |||||
Positive | 21 | 0 | 21 | Sensitivity | 80.77 (60.65–93.45) |
Negative | 5 | 171 | 176 | Specificity | 100 (97.87–100) |
Total | 26 | 171 | 197 | Positive predictive value | 100 (83.89–100) |
Negative predictive value | 97.16 (93.50–99.07) | ||||
One Step malaria pLDH | |||||
Positive | 16 | 0 | 16 | Sensitivity | 61.54 (40.57–79.77) |
Negative | 10 | 171 | 181 | Specificity | 100 (97.87–100) |
Total | 26 | 171 | 197 | Positive predictive value | 100 (79.41–100) |
Negative predictive value | 94.48 (90.07–97.32) | ||||
One Step malaria HRP-II | |||||
Positive | 25 | 6 | 31 | Sensitivity | 96.15 (80.36–99.90) |
Negative | 1 | 165 | 166 | Specificity | 96.49 (92.52–98.78) |
Total | 26 | 171 | 197 | Positive predictive value | 80.65 (62.53–92.55) |
Negative predictive value | 99.40 (96.69–99.98) | ||||
One Step malaria HRP-II + peripheral thick blood smear | |||||
Positive | 25 | 6 | 31 | Sensitivity | 96.15 (80.36–99.90) |
Negative | 1 | 165 | 166 | Specificity | 96.49 (92.52–98.78) |
Total | 26 | 171 | 197 | Positive predictive value | 80.65 (62.53–92.55) |
Negative predictive value | 99.40 (96.69–99.98) | ||||