Description | N | Value |
---|---|---|
Child characteristics | ||
Age (geometric mean, range) | 97 | 3.8 years (1; 12) |
Age < 60 months | 97 | 63 |
Female | 98 | 44 |
Nutritional status | ||
Height (mean ± 2SD) | 71 | 98 cm (69.2; 128.6) |
Weight (geometric mean ± 2SD) | 98 | 14.4 kg (7.7; 26.6) |
Stunted (children < 60 months)a | 45 | 13 (29%) |
Underweight (children < 60 months)a | 63 | 11 (17%) |
Low BMI-for-age (children > 60 months)b | 26 | 8 (31%) |
Admission | ||
Hospital admission (yes/no) | 98 | 60/38 |
Admission length (median, IQR) | 60 | 3 days (2; 4) |
Clinical malaria (uncomplicated/severe) | 98 | 68/30 |
Clinical co-infection on presentation (yes/no)c | 98 | 22/76 |
Laboratory parameters | ||
Malaria parasitaemia on presentation (geometric mean ± 2SD) | 98 | 40,326 IEs/µL (3465; 469,356) |
Haemoglobin on presentation (geometric mean ± 2SD) | 98 | 9.5 g/dL (6.7; 13.5) |
Anaemia level on presentation (no anaemia/mild/moderate)d | 98 | 24/60/14 |
Iron deficiency on day 42 (ferritin < 15 µg/L) | 52 | 4 |
Glucose-6-phosphate dehydrogenase deficiency (normal enzyme activity/partial defect/full defect)e | 54 | 39/4/11 |
Sickle cell genotype (AA/AC/AF/AS) | 98 | 85/8/2/3 |
Raised C-reactive protein on day 0 (> 5 mg/L) | 94 | 93 |
Raised α-1-acid glycoprotein on day 0 (> 1 g/L) | 92 | 90 |
Positive stool microscopy for anaemia-causing pathogenic organismsf | 74 | 4 |
Antimalarial treatment prior to hospital attendance | 98 | 19 |
Antimalarial treatment prescribed (quinine i.v. + artemether–lumefantrine follow-on/artemether–lumefantrine only) | 98 | 44/54 |