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Fig. 35 | Malaria Journal

Fig. 35

From: Systematic identification of plausible pathways to potential harm via problem formulation for investigational releases of a population suppression gene drive to control the human malaria vector Anopheles gambiae in West Africa

Fig. 35

Pathway 33 Animal health: Potentially decreased livestock defence response to pathogen from altered levels of endogenous RNA or protein in saliva of dsxFCRISPRh transgenics could lead to increased disease in livestock. Mosquito RNA injected from its saliva during biting could affect vector-host-parasite interactions [142,143,144]. The net effect of a population suppression gene drive would ultimately reduce this specific harm by reducing the density of the target species of mosquitoes, including transgenic ones

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Malaria Journal

ISSN: 1475-2875

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