Skip to main content

Table 1 2 × 2 factorial design of parent trial

From: Community acceptance of reactive focal mass drug administration and reactive focal vector control using indoor residual spraying, a mixed‐methods study in Zambezi region, Namibia

 

Human intervention

RACD*

(reactive case detection)

28 clusters

rfMDA

(reactive focal mass drug administration)

28 clusters

Mosquito intervention

No RAVC

A

B

(no reactive focal vector control)

RACD only arm

rfMDA only arm

28 clusters

14 clusters

14 clusters

RAVC

C

D

(reactive focal vector control)

RACD + RAVC arm

rfMDA + RAVC arm

28 clusters

14 clusters

14 clusters

  1. *RACD (reactive case detection): administering rapid diagnostic tests to people living within a 500 m radius of an index case; treating positives with artemether-lumefantrine and single dose primaquine
  2. rfMDA (reactive focal mass drug administration): presumptively treating individuals living within a 500 m radius around an index case using artemether-lumefantrine, without testing
  3. RAVC (reactive focal vector control): spraying long-acting insecticide, pirimiphos-methyl, on interior walls of sleeping structures in a 7-household radius around an index case