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Fig. 1 | Malaria Journal

Fig. 1

From: IFN-λ4 genetic variants influence clinical malaria episodes in a cohort of Kenyan children

Fig. 1

Sickle cell trait genotype and G6PD allelic determinant stratified by IFNL4 allele. The study subjects were divided into two groups based on presence or absence of an IFNL4-dG allele. Within each group, subjects were further stratified based on carriage of sickle cell trait (SCT) and Glucose-6-Phosphate (G6PD) deficiency. Most of the subjects, 67% for the IFNL4-dG allele group and 55% for the IFNL4-TT/TT genotype group had neither the G6PD deficiency allelic determinant nor were carriers of the sickle cell trait. On the contrary, only 3% of the subjects with the IFNL4-dG allele were both carriers of the sickle cell trait and G6PD deficiency allelic determinant, while the percentage of subjects that had both genes in the IFNL4-TT/TT genotype group was 1%

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