Fig. 1From: IFN-λ4 genetic variants influence clinical malaria episodes in a cohort of Kenyan childrenSickle cell trait genotype and G6PD allelic determinant stratified by IFNL4 allele. The study subjects were divided into two groups based on presence or absence of an IFNL4-dG allele. Within each group, subjects were further stratified based on carriage of sickle cell trait (SCT) and Glucose-6-Phosphate (G6PD) deficiency. Most of the subjects, 67% for the IFNL4-dG allele group and 55% for the IFNL4-TT/TT genotype group had neither the G6PD deficiency allelic determinant nor were carriers of the sickle cell trait. On the contrary, only 3% of the subjects with the IFNL4-dG allele were both carriers of the sickle cell trait and G6PD deficiency allelic determinant, while the percentage of subjects that had both genes in the IFNL4-TT/TT genotype group was 1%Back to article page