Fig. 2
From: IFN-λ4 genetic variants influence clinical malaria episodes in a cohort of Kenyan children
Incidence of URTIs and time to first infection in children from the CHAP prospective cohort study. The study subjects were grouped based on presence of a IFNL4-dG allele, dG/dG and dG/TT genotypes (n = 95) and compared with children that did not carry a dG allele, TT/TT genotype (n = 27). a Histograms showing the distribution of URTIs in the study population during the first 2 years of life presented based on IFNL4-rs368234815 polymorphism. The mean number of URTIs and standard deviation (SD) is included. The rate of URTI’s was 11.80% lower for those that had the IFNL4- TT/TT genotype relative to those that had an IFNL4-dG allele after adjusting for the number of visits (95% CI −32.76%, 14.46%; p-value: 0.355). b Kaplan–Meier survival curve showing time to first URTIs based on IFNL4-rs368234815 polymorphism. No significant difference between IFNL4-rs368234815 genotype was found (p-value:0.512)