Molecular surveillance of anti-malarial resistance pfcrt, pfmdr1, and pfk13 polymorphisms in African Plasmodium falciparum imported parasites to Wuhan, China

Table 2 Novel polymorphisms of pfmdr1 and pfcrt in Plasmodium falciparum isolates

Gene	Reference^a			Mutation^b			Number of isolates
Gene	Codon position	AA^c	Codon	AA^c	Codon	Base position	PCR positive	Sequencing	Mutation	Prevalence (%, 95% CI)
pfmdr1	87	L	tta	L	ttG	261	106	106	1	0.94(− 0.009 to 0.028)
	102	G	ggt	G	ggC	306			2	1.89(− 0.007 to 0.045)
	102	G	ggt	G	ggC/T	306			1	0.94(− 0.009 to 0.028)
	199	T	act	S	Tct	595			1	0.94(− 0.009 to 0.028)
pfcrt	136	Y	tat	N	Aat	332	90	90	2	2.22(− 0.009 to 0.053)
	140	Q	caa	K	cCa	344			1	1.11(− 0.011 to 0.033)
	140	Q	caa	Q/K	cA/Ca	344			1	1.11(− 0.011 to 0.033)

ISSN: 1475-2875