Skip to main content

Table 3 Prevalence of pfmdr1 polymorphisms in pre-treatment and post-treatment samples stratified by study site

From: Molecular surveillance for polymorphisms associated with artemisinin-based combination therapy resistance in Plasmodium falciparum isolates collected in Mozambique, 2018

pfmdr1a

Pre-treatment (N = 109)

Post-treatment (N = 48)

MEGA

MEZE

MEMP

MEIA

MEGA

MEZE

MEMP

MEIA

n = 39

n = 12

n = 20

n = 38

n = 22

n = 1

n = 3

n = 22

Y184

10 (25.6)

4 (33.3)

9 (45.0)

19 (50.0)

6 (27.3)

0 (0)

0 (0)

6 (27.3)

184Y/F

8 (20.5)

3 (25.0)

6 (30.0)

7 (18.4)

8 (36.4)

1 (100)

0 (0)

8 (36.4)

184F

21 (53.8)

5 (41.7)

5 (25.0)

12 (31.6)

8 (36.4)

0 (0)

3 (100)

8 (36.4)

NYD

18 (46.2)

7 (58.3)

15 (75.0)

26 (68.4)

14 (63.6)

1 (100)

0 (0)

14 (63.6)

NFD

29 (74.4)

8 (66.7)

11 (55.0)

19 (50.0)

16 (72.7)

1 (100)

3 (100)

16 (72.7)

  1. Samples are from both AL and ASAQ arms; MEGA: Massinga; MEZE: Moatize; MEMP: Montepuez; MEIA: Mopeia; three samples (two in the AL arm and one in the ASAQ arm) failed to amplify at day of failure at one or more loci and are not included in corresponding single nucleotide polymorphism and haplotype counts
  2. aPercentages may not sum to 100% because all possible haplotypes from mixed infections (both wild type and mutants) were included in the construction of haplotypes. Tests of significance not performed due to low sample sizes in two sites