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  1. The presence of ongoing local malaria transmission, identified though local surveillance and reported to regional WHO offices, by S-E Asian countries, forms the basis of national and international chemoprophyl...

    Authors: Ron H Behrens, Bernadette Carroll, Urban Hellgren, Leo G Visser, Heli Siikamäki, Lasse S Vestergaard, Guido Calleri, Thomas Jänisch, Bjørn Myrvang, Joaquim Gascon and Christoph Hatz
    Citation: Malaria Journal 2010 9:266
  2. Plasmodium falciparum is the major cause of malaria infection in the island of São Tomé, in the Republic of São Tomé and Príncipe (STP), with an incidence of 40 - 50% before 2004. Since 2004, through the coordina...

    Authors: Pei-Wen Lee, Chia-Tai Liu, Virgilio E do Rosario, Bruno de Sousa, Herodes Sacramento Rampao and Men-Fang Shaio
    Citation: Malaria Journal 2010 9:264
  3. Based on recent studies in Israel demonstrating that attractive toxic sugar bait (ATSB) methods can be used to decimate local anopheline and culicine mosquito populations, an important consideration is whether...

    Authors: Günter C Müller, John C Beier, Sekou F Traore, Mahamoudou B Toure, Mohamed M Traore, Sekou Bah, Seydou Doumbia and Yosef Schlein
    Citation: Malaria Journal 2010 9:262
  4. Improving the way artemether-lumefantrine (AL) is provided to patients attending clinics is critical to maximize the benefit of this new medicine. In 2007, a new initiative was launched in one part of Kenya to...

    Authors: Beatrice Wasunna, Dejan Zurovac, Jane Bruce, Caroline Jones, Jayne Webster and Robert W Snow
    Citation: Malaria Journal 2010 9:261
  5. Malaria is the most important public health problems in tropical and sub-tropical countries. Haem oxygenase (HO) enzyme and the pro-inflammatory cytokine tumour necrosis factor (TNF) have been proposed as one ...

    Authors: Jiraporn Kuesap, Kenji Hirayama, Mihoko Kikuchi, Ronnatrai Ruangweerayut and Kesara Na-Bangchang
    Citation: Malaria Journal 2010 9:260
  6. Malaria is still prevalent in rural communities of central Vietnam even though, due to deforestation, the primary vector Anopheles dirus is uncommon. In these situations little is known about the secondary vector...

    Authors: Cuong Do Manh, Nigel W Beebe, Van Nguyen Thi Van, Tao Le Quang, Chau Tran Lein, Dung Van Nguyen, Thanh Nguyen Xuan, Anh Le Ngoc and Robert D Cooper
    Citation: Malaria Journal 2010 9:259
  7. Multidrug-resistant Plasmodium is of major concern today. Effective vaccines or successful applications of RNAi-based strategies for the treatment of malaria are currently unavailable. An unexplored area in the f...

    Authors: Vikrant Nain, Shakti Sahi and Anju Verma
    Citation: Malaria Journal 2010 9:258
  8. The C-terminal region of Plasmodium falciparum merozoite surface protein-1 (PfMSP-119) is a leading malaria vaccine candidate antigen. However, the existence of different variants of this antigen can limit effica...

    Authors: Sedigheh Zakeri, Akram A Mehrizi, Samaneh Zoghi and Navid D Djadid
    Citation: Malaria Journal 2010 9:257
  9. Since 2001, there has been a tremendous increase in number of households protected by ITN and IRS in Ghana. However, there has not been evidence of a reduction in malaria cases as expected and reported deaths ...

    Authors: Andreas A Kudom and Ben A Mensah
    Citation: Malaria Journal 2010 9:256
  10. Most clinicians in developed, non-malaria endemic countries have limited or no experience in making clinical assessments of malaria disease severity and subsequent decisions regarding the need for parenteral t...

    Authors: René te Witt, Marlies E van Wolfswinkel, Pieter L Petit, Jaap J van Hellemond, Rob Koelewijn, Alex van Belkum and Perry JJ van Genderen
    Citation: Malaria Journal 2010 9:255
  11. Many countries are scaling up malaria interventions towards elimination. This transition changes demands on malaria diagnostics from diagnosing ill patients to detecting parasites in all carriers including asy...

    Authors: Ivor Harris, Wesley W Sharrock, Lisa M Bain, Karen-Ann Gray, Albino Bobogare, Leonard Boaz, Ken Lilley, Darren Krause, Andrew Vallely, Marie-Louise Johnson, Michelle L Gatton, G Dennis Shanks and Qin Cheng
    Citation: Malaria Journal 2010 9:254
  12. Efforts to ease administration and enhance acceptability of the oral anti-malarial artemether-lumefantrine (A-L) crushed tablet to infants and children triggered the development of a novel dispersible tablet o...

    Authors: Salim Abdulla, Baraka Amuri, Abdunoor M Kabanywanyi, David Ubben, Christine Reynolds, Steve Pascoe, Serge Fitoussi, Ching-Ming Yeh, Marja Nuortti, Romain Séchaud, Günther Kaiser and Gilbert Lefèvre
    Citation: Malaria Journal 2010 9:253
  13. The United Nations forecasts that by 2050, more than 60% of the African population will live in cities. Thus, urban malaria is considered an important emerging health problem in that continent. Remote sensing ...

    Authors: Vanessa Machault, Cécile Vignolles, Frédéric Pagès, Libasse Gadiaga, Abdoulaye Gaye, Cheikh Sokhna, Jean-François Trape, Jean-Pierre Lacaux and Christophe Rogier
    Citation: Malaria Journal 2010 9:252
  14. Malaria still remains a public health problem in some districts of Bhutan despite marked reduction of cases in last few years. To strengthen the country's prevention and control measures, this study was carrie...

    Authors: Kinley Wangdi, Pratap Singhasivanon, Tassanee Silawan, Saranath Lawpoolsri, Nicholas J White and Jaranit Kaewkungwal
    Citation: Malaria Journal 2010 9:251
  15. Safety data regarding exposure to artemisinin-based combination therapy in pregnancy are limited. This prospective cohort study conducted in Zambia evaluated the safety of artemether-lumefantrine (AL) in pregn...

    Authors: Christine Manyando, Rhoda Mkandawire, Lwipa Puma, Moses Sinkala, Evans Mpabalwani, Eric Njunju, Melba Gomes, Isabela Ribeiro, Verena Walter, Mailis Virtanen, Raymond Schlienger, Marc Cousin, Miriam Chipimo and Frank M Sullivan
    Citation: Malaria Journal 2010 9:249
  16. The current study was undertaken to determine the optimal wash-drying regimen and the effects of different washing procedures on the efficacy, and durability of four brands of newly introduced long-lasting ins...

    Authors: Francis K Atieli, Stephen O Munga, Ayub V Ofulla and John M Vulule
    Citation: Malaria Journal 2010 9:248
  17. Mutations in the dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes of Plasmodium falciparum are associated with resistance to anti-folate drugs, most notably sulphadoxine-pyrimethamine (SP)...

    Authors: Sankar Sridaran, Shannon K McClintock, Luke M Syphard, Karen M Herman, John W Barnwell and Venkatachalam Udhayakumar
    Citation: Malaria Journal 2010 9:247
  18. Entomopathogenic fungi infection on malaria vectors increases daily mortality rates and thus represents a control measure that could be used in integrated programmes alongside insecticide-treated bed nets (ITN...

    Authors: Ladslaus L Mnyone, Matthew J Kirby, Dickson W Lwetoijera, Monica W Mpingwa, Emmanuel T Simfukwe, Bart GJ Knols, Willem Takken and Tanya L Russell
    Citation: Malaria Journal 2010 9:246
  19. Prompt and correct diagnosis of malaria is crucial for accurate epidemiological assessment and better case management, and while the gold standard of light microscopy is often available, it requires both exper...

    Authors: José Carlos Sousa-Figueiredo, David Oguttu, Moses Adriko, Fred Besigye, Andrina Nankasi, Moses Arinaitwe, Annet Namukuta, Martha Betson, Narcis B Kabatereine and J Russell Stothard
    Citation: Malaria Journal 2010 9:245
  20. Intermittent preventive treatment in infants with sulphadoxine-pyrimethamine (IPTi-SP) reduces malaria morbidity by 20% to 33%. Potentially, however, this intervention may compromise the acquisition of immunit...

    Authors: Ulrike Buchholz, Robin Kobbe, Ina Danquah, Philipp Zanger, Klaus Reither, Harry H Abruquah, Martin P Grobusch, Peter Ziniel, Jürgen May and Frank P Mockenhaupt
    Citation: Malaria Journal 2010 9:244
  21. Whether Plasmodium falciparum, the agent of human malaria responsible for over a million deaths per year, causes fitness costs in its mosquito vectors is a burning question that has not yet been adequately resolv...

    Authors: Fred Aboagye-Antwi, Amadou Guindo, Amadou S Traoré, Hilary Hurd, Mamadou Coulibaly, Sékou Traoré and Frédéric Tripet
    Citation: Malaria Journal 2010 9:243
  22. Plasmodium falciparum apical membrane antigen-1 (AMA1) is a leading malaria vaccine candidate antigen that is expressed by sporozoite, liver and blood stage parasites. Since CD8+ T cell responses have been implic...

    Authors: Martha Sedegah, Yohan Kim, Bjoern Peters, Shannon McGrath, Harini Ganeshan, Jennylynn Lejano, Esteban Abot, Glenna Banania, Maria Belmonte, Renato Sayo, Fouzia Farooq, Denise L Doolan, David Regis, Cindy Tamminga, Ilin Chuang, Joseph T Bruder…
    Citation: Malaria Journal 2010 9:241
  23. Malaria is almost invariably ranked as the leading cause of morbidity and mortality in Africa. There is growing evidence of a decline in malaria transmission, morbidity and mortality over the last decades, esp...

    Authors: Valérie D'Acremont, Christian Lengeler and Blaise Genton
    Citation: Malaria Journal 2010 9:240
  24. Individual human subjects are differentially attractive to mosquitoes and other biting insects. Previous investigations have demonstrated that this can be attributed partly to enhanced production of natural re...

    Authors: James G Logan, Nina M Stanczyk, Ahmed Hassanali, Joshua Kemei, Antônio EG Santana, Karlos AL Ribeiro, John A Pickett and A Jennifer Mordue (Luntz)
    Citation: Malaria Journal 2010 9:239
  25. Plasmodium knowlesi is a cause of symptomatic and potentially fatal infections in humans. There are no studies assessing the detailed parasitological response to treatment of knowlesi malaria infections in man an...

    Authors: Cyrus Daneshvar, Timothy ME Davis, Janet Cox-Singh, Mohammad Z Rafa'ee, Siti K Zakaria, Paul CS Divis and Balbir Singh
    Citation: Malaria Journal 2010 9:238
  26. The main objective of this study was to assess the effectiveness of integrating the use of cell-phones into a routine malaria prevention and control programme, to improve the management of malaria cases among ...

    Authors: Pongthep Meankaew, Jaranit Kaewkungwal, Amnat Khamsiriwatchara, Podjadeach Khunthong, Pratap Singhasivanon and Wichai Satimai
    Citation: Malaria Journal 2010 9:237
  27. Molecular chaperones have been shown to be important in the growth of the malaria parasite Plasmodium falciparum and inhibition of chaperone function by pharmacological agents has been shown to abrogate parasite ...

    Authors: Rani Pallavi, Pragyan Acharya, Syama Chandran, Johanna P Daily and Utpal Tatu
    Citation: Malaria Journal 2010 9:236
  28. Malaria remains a major public health problem in Sub Saharan Africa, where widespread poverty also contribute to the burden of the disease. This study was designed to investigate the relationship between the p...

    Authors: Oyindamola B Yusuf, Babatunde W Adeoye, Oladimeji O Oladepo, David H Peters and David Bishai
    Citation: Malaria Journal 2010 9:235
  29. In areas of high transmission people often harbour multiple clones of Plasmodium falciparum, but even PCR-based diagnostic methods can only detect a fraction (the detectability, q) of all clones present in a host...

    Authors: Michael T Bretscher, Francesca Valsangiacomo, Seth Owusu-Agyei, Melissa A Penny, Ingrid Felger and Tom Smith
    Citation: Malaria Journal 2010 9:234
  30. Intercellular adhesion molecule-1 (ICAM-1) is a cytoadhesion molecule implicated in the pathogenesis of Plasmodium falciparum malaria. Elevated levels of soluble ICAM-1 (sICAM-1) have previously been reported wit...

    Authors: Christine M Cserti-Gazdewich, Walter H Dzik, Laura Erdman, Isaac Ssewanyana, Aggrey Dhabangi, Charles Musoke and Kevin C Kain
    Citation: Malaria Journal 2010 9:233
  31. In malaria-endemic areas, reliably establishing parasitaemia for diagnosis of malaria can be difficult. A retinopathy with some features unique to severe malaria with a predictive value on prognosis, has been ...

    Authors: Vera A Essuman, Christine T Ntim-Amponsah, Birgitte S Astrup, George O Adjei, Jorgen AL Kurtzhals, Thomas A Ndanu and Bamenla Goka
    Citation: Malaria Journal 2010 9:232
  32. The prevalence of Plasmodium falciparum and Plasmodium vivax malaria was very high in Corsica just before the Second World War. The last outbreak was in 1972 and the most recent indigenous case was in 2006.

    Authors: Céline Toty, Hélène Barré, Gilbert Le Goff, Isabelle Larget-Thiéry, Nil Rahola, Daniel Couret and Didier Fontenille
    Citation: Malaria Journal 2010 9:231
  33. Ontologies are rapidly becoming a necessity for the design of efficient information technology tools, especially databases, because they permit the organization of stored data using logical rules and defined t...

    Authors: Pantelis Topalis, Elvira Mitraka, Ioana Bujila, Elena Deligianni, Emmanuel Dialynas, Inga Siden-Kiamos, Marita Troye-Blomberg and Christos Louis
    Citation: Malaria Journal 2010 9:230
  34. Humoral immune responses play a key role in the development of immunity to malaria, but the host genetic factors that contribute to the naturally occurring immune responses to malarial antigens are not complet...

    Authors: Janardan P Pandey, Cristiane G Morais, Cor JF Fontes and Erika M Braga
    Citation: Malaria Journal 2010 9:229
  35. The diversity and abundance of Anopheles larvae has significant influence on the resulting adult mosquito population and hence the dynamics of malaria transmission. Studies were conducted to examine larval habita...

    Authors: Joseph M Mwangangi, Josephat Shililu, Ephantus J Muturi, Simon Muriu, Benjamin Jacob, Ephantus W Kabiru, Charles M Mbogo, John Githure and Robert J Novak
    Citation: Malaria Journal 2010 9:228
  36. Artemisinins are the newest class of drug approved for malaria treatment. Due to their unique mechanism of action, rapid effect on Plasmodium, and high efficacy in vivo, artemisinins have become essential comp...

    Authors: Judith H Waknine-Grinberg, Nicholas Hunt, Annael Bentura-Marciano, James A McQuillan, Ho-Wai Chan, Wing-Chi Chan, Yechezkel Barenholz, Richard K Haynes and Jacob Golenser
    Citation: Malaria Journal 2010 9:227
  37. The emergence of drug resistance is a major problem in malaria control. Combination of molecular genotyping and characterization of mutations or single nucleotide polymorphisms (SNPs) correlated with drug resi...

    Authors: Teferi Eshetu, Nicole Berens-Riha, Sintayehu Fekadu, Zelalem Tadesse, Robert Gürkov, Michael Hölscher, Thomas Löscher and Isabel Barreto Miranda
    Citation: Malaria Journal 2010 9:226
  38. Natural populations of the malaria mosquito Anopheles gambiae s.s. are exposed to large seasonal and daily fluctuations in relative humidity and temperature, which makes coping with drought a crucial aspect of th...

    Authors: Fred Aboagye-Antwi and Frédéric Tripet
    Citation: Malaria Journal 2010 9:225
  39. A recent school-based study in Benin showed that applying a policy of anti-malarial prescriptions restricted to parasitologically-confirmed cases on the management of fever is safe and feasible. Additional PCR...

    Authors: Jean-François Faucher, Agnès Aubouy, Todoégnon Béhéton, Patrick Makoutode, Grace Abiou, Justin Doritchamou, Pascal Houzé, Edgard Ouendo, Philippe Deloron and Michel Cot
    Citation: Malaria Journal 2010 9:224
  40. Glucose-6-phosphate dehydrogenase deficiency poses a significant impediment to primaquine use for the elimination of liver stage infection with Plasmodium vivax and for gametocyte clearance, because of the risk o...

    Authors: Melissa Kuwahata, Rushika Wijesinghe, Mei-Fong Ho, Anita Pelecanos, Albino Bobogare, Losi Landry, Hugo Bugora, Andrew Vallely and James McCarthy
    Citation: Malaria Journal 2010 9:223
  41. Insecticide-treated bed nets (ITNs) are an efficacious intervention for malaria prevention. During a national immunization campaign in Mozambique, vouchers, which were to be redeemed at a later date for free I...

    Authors: Alexandre Macedo de Oliveira, Adam Wolkon, Ramesh Krishnamurthy, Marcy Erskine, Dana P Crenshaw, Jacquelin Roberts and Francisco Saúte
    Citation: Malaria Journal 2010 9:222
  42. International travel and immigration have been related with an increase of imported malaria cases. This fact and climate change, prolonging the period favouring vector development, require an analysis of the m...

    Authors: Sandra Sainz-Elipe, Jose Manuel Latorre, Raul Escosa, Montserrat Masià, Marius Vicent Fuentes, Santiago Mas-Coma and Maria Dolores Bargues
    Citation: Malaria Journal 2010 9:221
  43. Variant surface antigens (VSA) expressed on the surface of Plasmodium falciparum-infected red blood cells constitute a key for parasite sequestration and immune evasion. In distinct malaria pathologies, such as p...

    Authors: Nabila Kheliouen, Firmine Viwami, Francis Lalya, Nicaise Tuikue-Ndam, Else C Eboumbou Moukoko, Christophe Rogier, Philippe Deloron and Agnès Aubouy
    Citation: Malaria Journal 2010 9:220
  44. Previously, Plasmodium knowlesi was not considered as a species of Plasmodium that could cause malaria in human beings, as it is parasite of long-tailed (Macaca fascicularis) and pig-tailed (Macaca nemestrina) ma...

    Authors: Thuy-Huong Ta Tang, Ana Salas, Marwa Ali-Tammam, María del Carmen Martínez, Marta Lanza, Eduardo Arroyo and Jose Miguel Rubio
    Citation: Malaria Journal 2010 9:219
  45. The evolution of drug resistance in malaria parasites highlights a need to identify and evaluate strategies that could extend the useful therapeutic life of anti-malarial drugs. Such strategies are deployed to...

    Authors: David L Smith, Eili Y Klein, F Ellis McKenzie and Ramanan Laxminarayan
    Citation: Malaria Journal 2010 9:217
  46. The planning and assessment of malaria interventions is complicated due to fluctuations in the burden of malaria over time. Recently, it has been reported that the burden of malaria in some parts of Africa has...

    Authors: Bruno P Mmbando, Lasse S Vestergaard, Andrew Y Kitua, Martha M Lemnge, Thor G Theander and John PA Lusingu
    Citation: Malaria Journal 2010 9:216

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