Skip to main content

Table 3 Intention to treat analysis of the effect of treatment with chloroquine 25 mg/kg

From: Paracetamol versus placebo in treatment of non-severe malaria in children in Guinea-Bissau: a randomized controlled trial

 

Paracetamol-group*

Placebo-group*

OR with confidence interval**

Day 0

100% (167/167)

100% (171/171)

 

Day 7

93.3% (152/163)

87.5% (147/168)

0.51 (0.21 - 1.15)

Day 14

84.4% (133/147)

79.6% (131/144)

0.72 (0.40 - 1.28)

Day 21

77.0% (115/126)

75.1% (118/125)

0.87 (0.52 - 1.43)

Day 28

73.6% (108/113)

71.9% (111/116)

0.89 (0.56 - 1.41)

Day 35

72.8% (97/98)

70.5% (102/104)

0.87 (0.55 - 1.37)

  1. The adequate clinical and parasitological response (ACPR) rates in the two treatment groups (see text):
  2. *) Cumulative percentages of children with ACPR during follow-up. The number of children with ACPR/total number of children is given in parenthesis (on day 7 children admitted to hospital on day 0 and children with early treatment failure are included in the denominator).
  3. **) Cumulative odds ratio of having ACPR in the group treated with placebo in relation to the paracetamol-group (Mantel-Haenszel weighted odds ratio, 95% confidence interval in brackets).
Back to article page

Malaria Journal

ISSN: 1475-2875

Contact us