Table 5 Fisher's exact test of association between polymorphisms and in vitro drug response, N = 31
Polymorphism vs. drug | p value |
|---|---|
pfcrt (K76T) vs. chloroquine | 0.001 |
pfATPase6 (D639G) vs. artesunate | 0.423 |
pfcrt (K76T) vs. artesunate | 1.000 |
pfmdr1 (N86Y) vs. artesunate | 1.000 |
pfmdr1 (Y184F) vs. artesunate | 1.000 |
pfmdr1 (N86Y) vs. chloroquine | 1.000 |
pfmdr1 (Y184F) vs. chloroquine | 0.104 |
pfmdr1 (N86Y) vs. amodiaquine | 1.000 |
pfmdr1 (Y184F) vs. amodiaquine | 0.253 |
pfmdr1 (N86Y) vs. quinine | 1.000 |
pfmdr1 (Y184F) vs. quinine | 1.000 |
pfmdr1 (double mutant) vs. artesunate | 0.577 |
pfmdr1 (double mutant) vs. chloroquine | 1.000 |
pfmdr1 (double mutant) vs. amodiaquine | 0.630 |
pfmdr1 (double mutant) vs. quinine | 1.000 |