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Table 3 Criteria used by reviewers to determine the requirement for dialysis (one or more required)

From: Laboratory prediction of the requirement for renal replacement in acute falciparum malaria

1.

Evolving hyperkalaemia (K greater than 5.5 mmol/L) and renal impairment.*

2.

Evolving acidosis (pH < 7.35, HCO3 < 15) and renal impairment.*

3.

Fluid overload not manageable by conservative measures and evolving renal impairment. *

4.

Uncontrolled seizures in the setting of renal impairment*

5.

Pericarditis in the setting of renal impairment*

6.

Dialysis initiated appropriately by treating physicians before above criteria were met (eg. significantly worsening renal impairment despite conservative measures)

  1. * Renal impairment: BUN greater than 30 mmol/L or plasma creatinine > 200 μmol/L.