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Table 1 Pvdhfr, pvdhps, pvmdr1 genotypes prevalence in P. vivax monoclonal infections

From: A new high-throughput method for simultaneous detection of drug resistance associated mutations in Plasmodium vivax dhfr, dhps and mdr1 genes

 

Number of P. vivax monoinfected samples (%)

dhfr genotype (codons 57/58/61-117-173)

 

   wild type:

 

FST-S-I

37 (52.9)

   double mutant type:

 

FR T-N-I

2 (2.9)

LR T-S-I

10 (14.3)

   quadruple mutant type:

 

LRM-T-I

21 (30.0)

dhps genotype (codons 382/383-553-647)

 

   wild type:

 

SC-A-A

1 (1.4)

   single mutant type:

 

SC-A-P

69 (98.6)

mdr1 genotype (codon 976)

 

   wild type:

 

Y

58 (82.9)

   mutant type:

 

F

12 (17.1)