From: Evaluation of dihydrofolate reductase and dihydropteroate synthetase genotypes that confer resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum in Haiti
Gene
Codon
Wild type codon(s) (amino acid)
Resistance codon(s) (amino acid)
dhfr
51
AAT, AAC (N)
ATT (I)
59
TGT (C)
CGT (R)
108
AGC (S)
AAC (N), ACC (T)
164
ATA(I)
TTA (L)
dhps
436
TCT (S)
GCT (A), TTT (F)
437
GCT (A)
GGT (G)
540
AAA (K)
GAA (E)