Figure 1

Artemether and dihydroartemisinin goodness-of-fit. The solid black line represents the line of identity, the local polynomial regression fitting for observations predicted above LLOQ is represented by the dashed black line and the local polynomial regression fitting for all observations is represented by the grey dashed line. The horizontal and vertical dashed black lines represent the lower limit of quantification (LLOQ). Clinical observations are represented by the black circles. Percentages mentioned in the diagnostic plots represent the percentages of the total amount of data in the particular subset.