Table 2 Demographic characteristics and laboratory findings of adult patients with Plasmodium knowlesi malaria
From: Laboratory markers of disease severity in Plasmodium knowlesi infection: a case control study
Variable | Uncomplicated malaria n = 93 | Severe malaria n = 17 | p-value |
|---|---|---|---|
Demographic characteristic | |||
Age, mean (95% CI), years | 43.44 (40.4 – 46.5) | 49.59 (43.24 – 55.94) | 0.11 |
Male sex, % | 68.8 | 70.6 | NA |
Iban ethnicity, % | 81.7 | 88.2 | NA |
Laboratory findings at admission | |||
White blood cell count, x 103/μl1 | 5.9 (5 – 7.55) | 8.7 (6.7 – 12.5) | 0.009 |
Neutrophils, mean (95% CI), % | 70.4 (68.8 – 71.9) | 75.1 (69.9 – 80.4) | 0.025 |
Monocytes, %1 | 2 (1 – 5) | 3 (2 – 4) | 0.69 |
Lymphocytes, mean (95% CI), % | 25.2 (23.8 – 26.6) | 21.2 (16.4 – 26) | 0.034 |
Parasite count, parasites/μl1 | 3843.5 (714.5 – 13030.5) | 94256 (18432 – 285768) | <0.0001 |
Parasite count, % IRBC1 | 0.3 (0.1- 0.7) | 2.5 (0.7 – 11.1) | <0.0001 |
Platelet count, x 103 platelets/μl1 | 69 (44 – 99) | 38 (26 – 48) | 0.0004 |
PCN count, cells/μl1 | 36 (0–128) | 563 (158 – 1388) | <0.0001 |