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Table 1 TLR2 Δ22, and GTn genotypes

From: Toll-like receptor polymorphisms and cerebral malaria: TLR2 Δ22 polymorphism is associated with protection from cerebral malaria in a case control study

Polymorphism

Genotype

Cerebral malaria n = 65

Uncomplicated malaria n = 52

p value

OR

95% CI

Δ22

W/W

36(56.3)

18(35.3)

.025I

0.42

0.20-0.98

 

W/D

21(32.8)

30(58.8)II

.005III

0.34

0.16-0.73

 

D/D

7(10.9)

3(5.9)

   

GTn

SM

12(19.4)

8(16.7)

   
 

MM

46(74.2)

34(70.8)

   
 

ML

4(6.4)

6(12.5)

   
  1. OR and 95% CI presented only for p values where p < 0.05
  2. I p value for dominant genotype test, WD/DD vs WW
  3. IIp = 0.065 for Hardy Weinberg Test of equilibrium, excess of heterozygotes
  4. III p value for heterozygote advantage genotype test, WD vs DD/WW
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Malaria Journal

ISSN: 1475-2875

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