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Table 2 Case definitions for clinical malaria

From: Randomized, controlled trial of the long term safety, immunogenicity and efficacy of RTS,S/AS02D malaria vaccine in infants living in a malaria-endemic region

Primary Case Definition

· The presence of P. falciparum asexual parasitaemia above 500 per μL) on Giemsa stained thick blood films AND

 

· the presence of fever (axillary temperature ≥ 37.5°C)

Secondary Case Definition

· The presence of P. falciparum asexual parasitaemia above 0 per μL) on Giemsa stained thick blood films AND

 

· the presence of fever (axillary temperature ≥ 37.5°C) or history of fever in the previous 24 hours