Table 3 Sensitivity, specificity, positive predictive value and negative predictive value of the HRP2 and pan pLDH-based test ( Plasmodium falciparum gametocytaemia was considered negative for P. falciparum )
Day | Sensitivity (95% CI) | Specificity (95% CI) | Positive predictive value | Negative predictive value | ||||
|---|---|---|---|---|---|---|---|---|
HRP2 | pLDH | HRP2 | pLDH | HRP2 | pLDH | HRP2 | pLDH | |
D0 | 100 | 100 | NR2 | NR2 | 100 | 100 | NR3 | NR3 |
(95.3–100%) | (95.3–100%) | (95.3–100%) | (95.3–100%) | |||||
D3 | 100 | 50 | 0 | 73.97 | 5.19 | 9.52 | NR3 | 96.43 |
(39.7–100%) | (6.8–93.2%) | (0.0–4.9%) | (62.4–83.6%) | (1.4–12.8%) | (1.2–30.4%) | (87.7–99.6%) | ||
D7 | NR1 | NR1 | 1.32 | 85.53 | 0 | 0 | 100 | 100 |
(0.1–7.1%) | (75.6–92.6%) | (0–4.8%) | (0–28.5%) | (2.5–100%) | (94.5–100%) | |||
D14 | NR1 | NR1 | 9.33 | 93.33 | 0 | 0 | 100 | 100 |
(3.8–18.3%) | (85.1–97.8%) | (0–5.3%) | (0–52.2%) | (59.0–100%) | (94.9–100%) | |||
D21 | 100 | 100 | 27.40 | 93.06 | 3.64 | 37.50 | 100 | 100 |
(15.8–100%) | (29.2–100%) | (17.6–39.1%) | (84.5–97.7%) | (0.4–12.5%) | (8.5–75.5%) | (83.2–100%) | (94.6–100%) | |
D28 | 100 | 88.89 | 39.44 | 96.87 | 4.44 | 80 | 100 | 98.41 |
(15.8–100%) | (51.8–99.7%) | (29.0–51.8%) | (89.2–99.6%) | (0.5–15.2%) | (44.4–97.5%) | (87.7–100%) | (91.5–99.9%) | |