From: G6PD deficiency in Plasmodium falciparum and Plasmodium vivax malaria-infected Cambodian patients
Patients’ characteristics | Plasmodium vivax | Plasmodium falciparum | P-value | |
---|---|---|---|---|
N | Â | 965 | 1443 | - |
Mean age in years (95% CI) | 26.5 (25.8-27.2) | 27.1 (26.3-27.7) | 0.27 | |
Age distribution (%) | <5Â years | 0.2 | 0.9 | <0.0001 |
5-14Â years | 9.2 | 11.9 | ||
>15Â years | 90.6 | 87.2 | ||
Sex ratio (% female) | Â | 23.4 | 18.1 | <0.0001 |
Mean G6PD activity in U/g Hb (95% CI) | 11.86 (11.57-12.15) | 11.45 (11.18-11.73) | 0.05 | |
G6PD Classes (%) | I (0% of normal) | 0.10% | 1.2% | <0.0001 |
II (0.1-10% of normal) | 4.9% | 9.2% | ||
III (10.1-60% of normal) | 5.6% | 6.0% | ||
IV (60.1-150% of normal) | 85.8% | 77.7% | ||
V (>150% of normal) | 3.6% | 6.0% | ||
Mean haemoglobin in g/dL (95% CI) | 10.2 (10.0-10.4) | 10.1 (9.9-10.2) | 0.4 | |
Mean white cell count in G/L (95% CI) | 4.03 (3.86-4.20) | 3.95 (3.81-4.09) | 0.53 | |
Haemoglobin electrophoresis profile (%) | Normal | 56.1 | 61.6 | 0.05 |
Hb E - homozygous | 6.1 | 4.9 | ||
Hb E - heterozygous | 33.5 | 30.1 | ||
Heterozygous E - α-thalassaemia | 4.1 | 3.3 | ||
Heterozygous Hb E - β-thalassaemia | 0.0 | 0.1 | ||
β-thalassaemia | 0.0 | 0.1 |