Figure 2

Living, dead and dying P. falciparum schizonts stained with JC-1. JC-1 staining of Plasmodium falciparum schizonts. The first row of images shows a living parasite as can be appreciated by the bright red signal at 568 nm indicating a functioning mitochondrion; the second row of images shows a dead parasite killed using anti-malarial drugs (no signal at 568 nm). In the third series only a faint red signal (sometimes difficult to detect) can be seen at 568 nm indicating that the mitochondrion membrane potential is disrupted and the parasite is dying.