Table 2 Solicited adverse events post-vaccination (day 0–7) in the Phase 1 Kenya study
|  | 50 μg MSP142/AS01 (N = 20*) | Rabies comparator (N = 10*) | ||||
|---|---|---|---|---|---|---|
G1 | G2 | G3 | G1 | G2 | G3 | |
Pain | ||||||
 Immunization 1 | 14 | 6 | 0 | 6 | 0 | 0 |
 Immunization 2 | 12 | 7 | 0 | 5 | 0 | 0 |
 Immunization 3 | 10 | 4 | 0 | 4 | 0 | 0 |
Redness | ||||||
 Immunization 1 | 1 | 0 | 0 | 0 | 0 | 0 |
 Immunization 2 | 3 | 0 | 0 | 2 | 0 | 0 |
 Immunization 3 | 0 | 0 | 1 | 0 | 0 | 0 |
Swelling | ||||||
 Immunization 1 | 6 | 0 | 0 | 2 | 0 | 0 |
 Immunization 2 | 3 | 0 | 0 | 2 | 0 | 0 |
 Immunization 3 | 1 | 0 | 1 | 1 | 0 | 0 |
Fever | ||||||
 Immunization 1 | 0 | 0 | 0 | 0 | 0 | 0 |
 Immunization 2 | 1 | 0 | 0 | 0 | 0 | 0 |
 Immunization 3 | 1 | 0 | 0 | 0 | 0 | 0 |
Fatigue | ||||||
 Immunization 1 | 2 | 3 | 0 | 1 | 0 | 0 |
 Immunization 2 | 1 | 1 | 0 | 1 | 0 | 0 |
 Immunization 3 | 2 | 0 | 0 | 0 | 0 | 0 |
Nausea | ||||||
 Immunization 1 | 3 | 0 | 0 | 1 | 0 | 0 |
 Immunization 2 | 0 | 1 | 0 | 0 | 0 | 0 |
 Immunization 3 | 0 | 0 | 0 | 0 | 0 | 0 |
Headache | ||||||
 Immunization 1 | 8 | 4 | 0 | 1 | 0 | 0 |
 Immunization 2 | 3 | 0 | 1 | 0 | 0 | 0 |
 Immunization 3 | 4 | 2 | 0 | 0 | 1 | 0 |
Malaise | ||||||
 Immunization 1 | 2 | 1 | 0 | 0 | 0 | 0 |
 Immunization 2 | 2 | 3 | 0 | 0 | 0 | 0 |
 Immunization 3 | 1 | 1 | 0 | 0 | 0 | 0 |
Myalgia | ||||||
 Immunization 1 | 1 | 0 | 0 | 1 | 0 | 0 |
 Immunization 2 | 1 | 2 | 0 | 0 | 0 | 0 |
 Immunization 3 | 1 | 0 | 0 | 0 | 0 | 0 |
Joint Pain | ||||||
 Immunization 1 | 2 | 1 | 0 | 1 | 0 | 0 |
 Immunization 2 | 1 | 2 | 0 | 0 | 0 | 0 |
 Immunization 3 | 1 | 0 | 0 | 1 | 0 | 0 |