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Table 3 Treatment responses on day 28

From: Artesunate-amodiaquine efficacy in Congolese children with acute uncomplicated falciparum malaria in Brazzaville

 

Total

Age

Residence

  

≤ 5 yrs old

> 5 yrs old

Urban area

Suburban area

Number of patients: N

197

96

101

125

72

PCR uncorrected responses on day 28

Withdrawn + Lost-to-follow-up, N (%)

15 (7.6)

10 (10.4)

5 (5)

11 (8.8)

4 (8.1)

Eligible; N (%)

182 (92.4)

86 (89.6)

96 (95)

114 (91.2)

68 (91.9)

Failure; N (%)

31 (17)

20 (23.3)

11 (11.5)

18 (15.8)

13 (19.1)

ETF; N (%)

1 (0.5)

0

1 (1)

1 (0.9)

0

LCF; N (%)

14 (7.7)

10 (11.2)

4 (4.2)

9 (7.9)

5 (7.4)

LPF; N (%)

16 (8.8)

10 (11.2)

6. (6.3)

8 (7)

8 (11.8)

ACPR; N (%)

151 (83)

66 (76.7)

85 (88.5)

96 (84.2)

55 (80.9)

PCR corrected responses on day 28

Withdrawn + Lost-to-follow-up + reinfection + not analyzed; N (%)

37 (18.8)

26 (27.1)

11 (10.9)

24 (19.2)

13 (18.1)

Eligible; N (%)

160 (81.2)

70 (72.9)

90 (89.1)

101 (80.8)

59 (81.9)

Failure; N (%)

9 (5.6)

4 (5.7)

5 (5.6)

5 (5)

4 (6.8)

ETF; N (%)

1 (0.6)

0

1 (1.1)

1 (1)

0

Recrudescence; N (%)

8 (5)

4 (5.7)

4 (4.5)

4 (4)

4 (6.8)

ACPR; N (%)

151 (94.4)

66 (94.3)

85 (94.4)

96 (95)

55 (93.2)

Recrudescence; N

8

4

4

4

4

 

Reinfection; N

10

7

3

3

7

  1. N, Number; ACPR, adequate clinical and parasitological response; LPF, late parasitological failure; LCF, late clinical failure; ETF, early treatment failure.