Table 3 CareStart™ and PCR sensitivity, specificity and predictive values
CS Diagnostic Kit | Microscopy | PCR | ||||||
|---|---|---|---|---|---|---|---|---|
P. falciparum* | P. vivax | P. falciparum* | P.vivax | |||||
Positive | Negative | Positive | Negative | Positive | Negative | Positive | Negative | |
Positive | 54 | 2 | 59 | 0 | 56 | 0 | 59 | 0 |
Negative | 7 | 113 | 6 | 115 | 7 | 113 | 6 | 113 |
Sensitivity (95% IC)% | 88.52 (78.16, 94.33) | 90.77 (81.29, 95.7) | 88.89 (78.8, 94.51) | 90.77 (81.29, 95.7) | ||||
Specificity (95% IC)% | 98.26 (93.88, 99.52) | 100 (96.77, 100) | 100 (96.71, 100) | 100 (96.71, 100) | ||||
Positive Predictive Value (95% IC)% | 96.43 (87.88, 99.02) | 100 (93.89, 100) | 100 (93.58, 100) | 100 (93.89, 100) | ||||
Negative Predictive Value (95% IC)% | 94.17 (88.45, 97.15) | 95.04 (89.6, 97.71) | 94.17 (88.45, 97.15) | 94.96 (89.44, 97.67) | ||||
Diagnostic Accuracy (95% IC)% | 94.89 (90.57, 97.29) | 96.67 (92.92, 98.46) | 96.02 (92.02, 98.06) | 96.63 (92.84, 98.45) | ||||
Cohen’s kappa (Unweighted) | 0.89 (0.74, 1.03) | 0.93 (0.78,1.07) | 0.91 (0.76, 1.06) | 0.93 (0.78, 1.07) | ||||