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Figure 2 | Malaria Journal

Figure 2

From: Chitinase 3-like 1 is induced by Plasmodium falciparum malaria and predicts outcome of cerebral malaria and severe malarial anaemia in a case–control study of African children

Figure 2

Human PBMCs produce CHI3L1 upon stimulation with P. falciparum . PBMCs were exposed to medium alone, uninfected red blood cells (RBCs; negative control), P. falciparum infected RBCs (Pf), or LPS (positive control) for 8 and 24 hrs. (A) Chi3l1 mRNA was assessed by quantitative real-time PCR, and (B) CHI3L1 concentration in supernatants was measured by ELISA. Graphs represent pooled data from at least 3 independent experiments using different PBMC donors. Data are presented as medians with interquartile ranges. *p < 0.05, Kruskal-Wallis test with Dunn’s post-tests.

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Malaria Journal

ISSN: 1475-2875

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