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Figure 6 | Malaria Journal

Figure 6

From: High-throughput tri-colour flow cytometry technique to assess Plasmodium falciparum parasitaemia in bioassays

Figure 6

SGI estimation agreement analysis and status of parasites in the ADCI assay. Nineteen (19) different IgG samples from Ghanaian children were tested in the ADCI assay on different days. Bland-Altman agreement statistical test between SGI estimated by: A) Microscopy and mitotracker red alone staining (bias = 27.62), B) Tri-colour technique and microscopy (bias = -1.60) and C) Tri-colour technique and mitotracker red alone staining (bias = 26.02). The upper and lower 95% confidence limits of the bias between respective methods being compared are indicated as two dotted lines. D) Tri-colour estimation of total parasitaemia, live and dead (and/or compromised) parasites for each of the 19 samples tested in the ADCI assay. Values are plotted ± standard deviation for duplicate wells. SGI: specific growth inhibition index; ADCI: antibody dependent cellular inhibition.

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