From: Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquine
drug
logD5.2
Vol(Ã…3) (base)
surface area (Ã…2) (base)
protons (positive charges)
CQ
-3.44
1010
606
2
DCQ
-4.61
910
555
AQ
-1.06
996
568
DAQ
-2.54
930
554
VP
0.59
1340
734
1