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Table 1 Susceptibilities of four P. falciparum strains to CQ and FQ. IC50 and IC90 are given ± the standard deviation. The number of experiments is in brackets

From: Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure

  

IC50 (nM)

IC90 (nM)

Strain HB3

CQ

21.83 ± 4.5 (10)

45.74 ± 13.9 (10)

 

FQ

20.17 ± 6.0 (10)

28.61 ± 7.3 (10)

Strain Dd2

CQ

61.81 ± 28.7 (4)

166.75 ± 45.2 (4)

 

FQ

18.88 ± 4.3 (4)

28.40 ± 7.9 (4)

Strain 3D7

CQ

12.6 ± 5.9 (33)

35.9 ± 16 (30)

 

FQ

7.5 ± 3.3 (36)

13.1 ± 7.6 (36)

Strain W2

CQ

148.8 ± 60.3 (34)

> 500 (34)

 

FQ

13.2 ± 4.1 (38)

29 ± 11.5 (35)