Efficacy of three artemisinin combination therapies for the treatmentof uncomplicated Plasmodium falciparum malaria in the Republic of Congo

Table 2 Proportion of recurrent parasitaemia and treatment failures at 28 days after treatment, Kindamba, ROC, 2004

	AS + AQ			AS + SP			AL			χ²
	n	%	95% CI	n	%	95% CI	n	%	95% CI	P
No PCR	97			85			100
ACPR	66	68.0	57.8–77.1	64	75.3	64.7–84.0	87	87.0	78.8–92.9	0.006
Parasites/fever	19	19.6	12.2–28.9	9	10.6	5.0–19.1	5	5.0	1.6–11.3
Parasites/no fever	12	12.4	6.6–20.6	12	14.1	7.5–23.4	8	8.0	3.5–15.2
Recurrent parasitaemia	31	32.0	22.9–42.2	21	24.7	16.0–35.3	13	13.0	7.1–21.2	0.006
PCR adjusted	67			71			87
ACPR	66	98.5	92.0–100	64	90.1	80.7–95.9	87	100.0	95.8–100	0.003
LCF	0	0.0	0–5.4	2	2.8	0.3–9.8	0	0.0	0–4.2
LPF	1	1.5	0–8.0	5	7.0	2.3–15.7	0	0.0	0–4.2
Treatment failure	1	1.5	0.0–8.0	7	9.9	19.3–4.1	0	0.0	0.0–5.2	0.003

ISSN: 1475-2875