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Table 3 The derivation of the patients status on the last day of follow, which is required for survival analysis

From: World Antimalarial Resistance Network I: Clinical efficacy of antimalarial drugs

Key Variable

Status

Species at Enrollment *

Outcome †

Species at Failure *

PCR Correction **

PF Unadjusted by genotyping φ

PF Recrudescence φ

PV Recurrence φ

1–5

0

N/A

N/A

0

0

0

Any

1–6

1

N/A

1

1

0

Any

1–6

2

N/A

0

0

1

1 or 3 or 4

7–12

1 or 4

1

1

0

0

1 or 3 or 4

7–12

1 or 4

2

1

1

0

1 or 3 or 4

7–12

1 or 4

3

1

§

0

1 or 3 or 4

7–12

3

1

1

0

1

1 or 3 or 4

7–12

3

2

1

1

1

1 or 3 or 4

7–12

3

3

1

§

1

1 or 3 or 4

7–12

2 or 5

N/A

0

0

1

1 or 3 or 4

7–12

6

N/A

0

0

0

2 or 5

7–12

1 or 4

N/A

1

-

0

2 or 5

7–12

3

N/A

1

-

1

2 or 5

7–12

2 or 5

N/A

0

-

1

2 or 5

7–12

6

N/A

0

-

0

1–5

13–20

N/A

N/A

0

0

0

1–5

21

N/A

N/A

-

-

-

  1. * 1 = Pf monoinfection; 2 = Pv monoinfection; 3 = Pf + Pv mixed; 4 = Pf mixed, but Pv not present; 5 = Pv mixed, but Pf not present, 6 = Other Species not Pf or Pv
  2. ** 1 = Reinfection, 2 = Recrudescence, 3 = Unavailable/Uninterpretable; N/A = Not applicable
  3. † See Table 2 φ 0 = Not a failure; 1 = Failure
  4. §As yet there is no consensus as to how to deal with indeterminate PCR results, although strategies to deal with these are being developed. Currently these are excluded from the PCR corrected analysis.