Table 1 Main characteristics of the area and intervention in Ifakara and Manhiça
Ifakara | Manhiça | |
|---|---|---|
Years of intervention | 1999–2001 | 2002–2004 |
Number of children randomized | 701 | 1503 |
Incidence of malaria in placebo group a | 0.36 | 0.43 |
EIR* | 29 | 38 |
Transmission | Perennial | Perennial with marked seasonality |
IPTi regimen** | 2, 3, 9 | 3, 4, 9 |
Iron supplementation** | 2–6 | - |
1st line Malaria Treatment during study | SP | SP + AQ |
ITN use | 68% | 0 |
HIV seroprevalence (at ANC) | 6.7% | 19% |
Hb AS prevalence *** | 12% | 0 |
SP parasitological sensitivity# | 69% (62/90) | 78.6% (55/70) |
SP ACR# | 94% (84/89) | 83% (67/81) |