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Table 3 Comparison ofSelected Serum Biomarker Median Ratios between the three Study Groups

From: Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children

PRO-INFLAMMATORY OR ANGIOSTATIC vs. ANTI-INFLAMMATORY OR ANGIOGENIC BIOMARKER MEDIAN RATIO

CM

SMA

NM

OVERALL P VALUE

TNF-α : IL-10

4.11

3.22

3.18

NSS

TNF-α : IL-8

2.48

2.29

2.26

NSS

TNF-α : PDGFbb

1.64 × 10-2

1.54 × 10-2

1.56 × 10-2

NSS

IP-10 : IL-10

34.85

18.86

23.23

NSS

IP-10 : IL-8

2.31 × 10-1

1.27 × 10-1

1.63 × 10-1

NSS

IP-10 : PDGFbb

57.52

26.41

32.73

NSS

  1. Median ratios of serum levels of pro-inflammatory/angiostatic versus anti-inflammatory/angiogenic biomarkers were compared between the 3 disease groups; P < 0.05 considered statistically significant; NSS, not statistically significant.