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Figure 2 | Malaria Journal

Figure 2

From: Malarial pigment haemozoin, IFN-gamma, TNF-alpha, IL-1beta and LPS do not stimulate expression of inducible nitric oxide synthase and production of nitric oxide in immuno-purified human monocytes

Figure 2

HZ-fed immuno-purified human monocytes transmit the IFN-gamma signal into the cell with subsequent JAK2 phosphorylation. Adherent monocytes were fed or not with native P. falciparum HZ for 24 h. Phosphorylated JAK-2 from control and HZ-fed monocytes treated or not with IFN-gamma was immunoprecipitated with anti-phosphotyrosine and probed with anti-JAK-2 in Western blot. One representative experiments out of 3 with similar results.

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Malaria Journal

ISSN: 1475-2875

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