Table 2 Summary of Model Parameters and Symbols
Parameter Description | Parameter Symbol | Value |
|---|---|---|
Definitions for equations | ||
Susceptible population at age (a) | S(a) | N/A |
Asymptomatic population at age (a) | A(a) | N/A |
Age-dependent rate of natural clearance of parasitaemia at age (a) | r(a) | N/A |
Age-dependent rate of development of clinical disease which is then treated at age (a) | c(a) | N/A |
Protective Efficacy | PE | N/A |
Fixed parameters | ||
Rate of development of clinical disease in the absence of immunity | φ | 0.9 |
Mean number of infections after which full immunity to clinical disease occurs | μ | 5 |
Parameters which determine the number of infections after which full immunity to clinical disease occurs | α1 and α2 | 1 |
Mean number of infections after which full parasite immunity occurs | ω | 50 |
Protection offered by ITN use | θ | 0.5 |
Variable parameters between sites | ||
Force of infection | λ(a) | See table 3 |
Drug action reducing the force of infection | σ | See table 3 |