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Table 6 Sensitivity analysis of maternal immunity function on models predictions of PE with (a) no maternal immunity function, (b) with fixed non-parametric function used in the paper (Baseline) and (c) function based on maternal immunity to severe disease.

From: Can changes in malaria transmission intensity explain prolonged protection and contribute to high protective efficacy of intermittent preventive treatment for malaria in infants?

Study Site

Observed PE (%, 95% CI)

Model PE (%)

  

(a) No immunity

(b) Baseline

(c) Alternative based on immunity to severe disease

Ifakara

58.8 (40.8–71.3)

32.4

23.0

26.4

Manhica

20.1 (2.1–34.9)

38.6

32.0

34.0

Navrongo

29.3 (17.7–39.5)

38.5

31.9

34.1

Lamebarene

22.0 (-25.4–51.5)

28.2

23.6

26.0

Kumasi

20.9 (8.9–31.3)

38.0

25.9

30.3

Tamale

33.3 (20.7–43.8)

29.7

24.9

27.4