Comparison of Plasmodium falciparum allelic frequency distribution in different endemic settings by high-resolution genotyping

Table 2 Diversity of msp1 and msp2 in samples from Papua New Guinea and Tanzania

	Papua New Guinea		Tanzania
	*msp2*	*msp1*	*msp2*	*msp1*
Number of samples (n)	108	108	115	115
Number of alleles	35	24	76	29
Frequency of most common allele	15.08%	16.28%	11.21%	20.57%
Number of clones	199	215	428	350
Mean MOI*	1.84	1.99	3.72^§	3.04^§
H_E**	0.933	0.918	0.965	0.917
P = Σp_i²	0.07	0.084	0.036	0.085
Combined probability***	0.0058		0.003

* MOI = mean multiplicity of infection
** H_E = expected heterozygosity. This is defined as the probability that two randomly chosen alleles are different in the population.
*** The combined probability that two independent clones share the same genotype for both marker genes was calculated by multiplying the probabilities P for both marker genes.
^§ Indicates significant difference between mean MOI of msp1 and msp2 (p < 0.001)

ISSN: 1475-2875