Accuracy of a rapid diagnostic test on the diagnosis of malaria infection and of malaria - attributable fever during low and high transmission season in Burkina Faso

Table 7 Estimated diagnostic accuracy of RDT for malaria - attributable fever during the low and high transmission seasons

Age	Febrile	Malaria-attributable		Not malaria-attributable		SE	SP	PPV	NPV
(years)	N	TP (a)	FN (b)	FP (c)	TN (d)
Low transmission (dry) season
< 1	143	4.4	0.2	35.9	102.4	95	74	11	99.8
1 - 4	299	8.8	0.5	88.2	201.5	94	70	9	99.7
5 - 14	130	4.0	0.3	39.9	85.7	93	68	9	99.7
15+	280	2.5	0.3	46.2	230.9	89	83	5	99.9
All	852	19.8	1.3	210.3	620.6	94	75	9	99.8
High transmission (rainy) season
< 1	159	113.6	3.3	25.5	16.7	97	40	82	84
1 - 4	504	293.2	7.7	130.2	72.9	97	36	69	90
5 - 14	275	113.4	4.0	99.6	58.1	97	37	53	94
15+	379	45.7	1.4	74.4	257.4	97	78	38	99.4
All	1317	565.8	16.4	329.7	405.1	97	55	63	96

N: number of febrile patients in each age-parasite density combination.
TP, FN, FP, TN: expected number of true positives, false negatives, false positives and true negatives of the RDT for clinical malaria diagnosis among the N febrile cases in each age-parasite density combination. Estimates obtained from N, AF and Prob RDT + (see methods). Numbers presented are rounded to 1 decimal place; actual calculations based on a better numerical precision.
SE, SP, PPV, NPV: estimated sensitivity, specificity, positive predictive value, negative predictive value of RDT for clinical malaria.

ISSN: 1475-2875